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Structure of ellipticine in complex with a 6-bp DNA

Analyse Structure of ellipticine in complex with a 6-bp DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1Z3F
Type
DNA
Length
12 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-D(*CP*GP*AP*TP*CP*G)-3'
Ligands
EL, CO

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B5'-D(*CP*GP*AP*TP*CP*G)-3'dna6——

Ligands and binding sites

  • EL · Ellipticine · ligand · 2 copies · chains A, B
  • CO · Cobalt (II) ion · metal · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 298 Ų buried · 21 hydrogen bonds · nucleic-nucleic

Compared structures

  • 1Z3F · Structure of ellipticine in complex with a 6-bp DNA · the same entry in another collection · chain A against A, TM-score 1.00

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