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Structure of S-ADENOSYLMETHIONINE:TRNA ribosyltransferase- isomerase (quea)

Analyse Structure of S-ADENOSYLMETHIONINE:TRNA ribosyltransferase- isomerase (quea) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1YY3
Type: protein
Length: 630 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: S-ADENOSYLMETHIONINE:TRNA ribosyltransferase- isomerase
EC: 5.-.-.-
UniProt: O32054
Pockets: 6 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	S-ADENOSYLMETHIONINE:TRNA ribosyltransferase- isomerase (EC 5.-.-.-)	protein	315	25% helix, 25% strand	O32054

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	272	0.54	0.76	46	empty
2	233	0.50	0.75	42	empty
3	119	0.48	0.79	24	empty
4	79	0.46	0.81	20	empty
5	68	0.33	0.76	16	empty

Compared structures

1YY3 · Structure of S-Adenosylmethionine:tRNA Ribosyltransferase-Isomerase (QueA) · the same entry in another collection · chain A against A, TM-score 1.00
O32054 · AlphaFold monomer V2.0 prediction for S-ADENOSYLMETHIONINE:TRNA… · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O32054
Elsewhere: RCSB PDB 1YY3 · PDBe 1YY3 · UniProt O32054

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