Research workbench

Structure of the ferrous co complex of NP4 from rhodnius prolixus at pH 7.0

Analyse Structure of the ferrous co complex of NP4 from rhodnius prolixus at pH 7.0 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1YWC
Type: protein
Length: 184 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nitrophorin 4
UniProt: Q94734
Ligands: HEM, CMO
Pockets: 1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nitrophorin 4	protein	184	14% helix, 45% strand	Q94734

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A
CMO · Carbon monoxide · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	352	0.77	0.87	39	HEM, CMO

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1YWC · Structure of the ferrous CO complex of NP4 from Rhodnius Prolixus at pH 7.0 · the same entry in another collection · chain A against A, TM-score 1.00
Q94734 · AlphaFold monomer V2.0 prediction for nitrophorin-4 (Q94734) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q94734
Elsewhere: RCSB PDB 1YWC · PDBe 1YWC · UniProt Q94734

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.