Research workbench
Structure of the conserved protein of unknown function PA3696 from pseudomonas aeruginosa
Analyse Structure of the conserved protein of unknown function PA3696 from pseudomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YOX
- Type
- protein
- Length
- 1,179 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein PA3696
- UniProt
- Q9HXU4
- Pockets
- 15 · best druggability 0.75
Structure
x-ray diffraction · 6 distinct chains · 12% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein PA3696 | protein | 190 | 13% helix, 55% strand | Q9HXU4 |
| B | Hypothetical protein PA3696 | protein | 195 | 11% helix, 56% strand | Q9HXU4 |
| C | Hypothetical protein PA3696 | protein | 196 | 13% helix, 55% strand | Q9HXU4 |
| D | Hypothetical protein PA3696 | protein | 209 | 10% helix, 54% strand | Q9HXU4 |
| E | Hypothetical protein PA3696 | protein | 203 | 13% helix, 58% strand | Q9HXU4 |
| F | Hypothetical protein PA3696 | protein | 186 | 13% helix, 57% strand | Q9HXU4 |
Pockets
15 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 996 | 0.75 | 0.78 | 74 | empty |
| 2 | 80 | 0.74 | 0.97 | 16 | empty |
| 3 | 441 | 0.72 | 0.83 | 40 | empty |
| 4 | 140 | 0.66 | 0.87 | 30 | empty |
| 5 | 267 | 0.63 | 0.81 | 37 | empty |
Interfaces
11 interfaces between chains.
- D–E · 1587 Ų buried · 25 hydrogen bonds · protein-protein
- D–F · 1405 Ų buried · 24 hydrogen bonds · protein-protein
- B–C · 1319 Ų buried · 24 hydrogen bonds · protein-protein
- A–B · 1253 Ų buried · 19 hydrogen bonds · protein-protein
- A–C · 1194 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 26 modified (engineered).
Compared structures
- 1YOX · Structure of the conserved Protein of Unknown Function PA3696 from Pseudomonas aeruginosa · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HXU4
- Elsewhere: RCSB PDB 1YOX · PDBe 1YOX · UniProt Q9HXU4
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