Research workbench
Re-engineering topology of the homodimeric rop protein into a single- chain 4-helix bundle
Analyse Re-engineering topology of the homodimeric rop protein into a single- chain… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YO7
- Type
- protein
- Length
- 240 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein rop
- UniProt
- P03051
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 87% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Regulatory protein rop | protein | 120 | 87% helix, 0% strand | P03051 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.34 | 0.76 | 11 | empty |
| 2 | 58 | 0.31 | 0.76 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 743 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 1YO7 · Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle · the same entry in another collection · chain A against A, TM-score 1.00
- P03051 · AlphaFold monomer V2.0 prediction for regulatory protein rop (P03051) · a predicted model of the same protein · chain A against A, TM-score 0.47
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03051
- Elsewhere: RCSB PDB 1YO7 · PDBe 1YO7 · UniProt P03051
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