Research workbench
Crystal structure of the putative carbonyl reductase sniffer of caenorhabditis elegans
Analyse Crystal structure of the putative carbonyl reductase sniffer of caenorhabditis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YO6
- Type
- protein
- Length
- 1,413 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative carbonyl reductase sniffer
- UniProt
- P90780
- Pockets
- 10 · best druggability 0.73
Structure
x-ray diffraction · 6 distinct chains · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative carbonyl reductase sniffer | protein | 237 | 45% helix, 16% strand | P90780 |
| B | Putative carbonyl reductase sniffer | protein | 235 | 43% helix, 15% strand | P90780 |
| C | Putative carbonyl reductase sniffer | protein | 240 | 45% helix, 15% strand | P90780 |
| D | Putative carbonyl reductase sniffer | protein | 236 | 42% helix, 16% strand | P90780 |
| E | Putative carbonyl reductase sniffer | protein | 235 | 44% helix, 15% strand | P90780 |
| F | Putative carbonyl reductase sniffer | protein | 230 | 40% helix, 15% strand | P90780 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 623 | 0.73 | 0.80 | 71 | empty |
| 2 | 754 | 0.72 | 0.78 | 66 | empty |
| 3 | 570 | 0.64 | 0.75 | 48 | empty |
| 4 | 243 | 0.59 | 0.80 | 34 | empty |
| 5 | 281 | 0.57 | 0.77 | 36 | empty |
Interfaces
7 interfaces between chains.
- C–D · 1951 Ų buried · 30 hydrogen bonds · protein-protein
- E–F · 1951 Ų buried · 35 hydrogen bonds · protein-protein
- A–B · 1931 Ų buried · 34 hydrogen bonds · protein-protein
- A–C · 625 Ų buried · 13 hydrogen bonds · protein-protein
- B–E · 260 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 1YO6 · Crystal Structure of the putative Carbonyl Reductase Sniffer of Caenorhabditis elegans · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P90780
- Elsewhere: RCSB PDB 1YO6 · PDBe 1YO6 · UniProt P90780
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