Research workbench
Crystal structure of a mutant form of the mycobacterial adenylyl cyclase RV1625C
Analyse Crystal structure of a mutant form of the mycobacterial adenylyl cyclase RV1625C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1YK9
- Type
- protein
- Length
- 184 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenylate cyclase
- EC
- 4.6.1.1
- UniProt
- O30820
- Pockets
- 4 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 20% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Adenylate cyclase (EC 4.6.1.1) | protein | 184 | 20% helix, 23% strand | O30820 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 241 | 0.62 | 0.81 | 33 | empty |
| 2 | 94 | 0.52 | 0.83 | 22 | empty |
| 3 | 143 | 0.49 | 0.79 | 26 | empty |
| 4 | 55 | 0.28 | 0.74 | 13 | empty |
Compared structures
- 1YK9 · Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O30820
- Elsewhere: RCSB PDB 1YK9 · PDBe 1YK9 · UniProt O30820
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