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C-terminal domain of mouse brain tubby protein

Analyse C-terminal domain of mouse brain tubby protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1C8Z
Type: protein
Length: 265 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tubby protein
UniProt: P50586
Ligands: PO4
Pockets: 4 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tubby protein	protein	265	13% helix, 36% strand	P50586

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	150	0.57	0.82	22	empty
2	61	0.36	0.78	12	PO4
3	95	0.35	0.74	22	empty
4	59	0.35	0.78	13	empty

Compared structures

1C8Z · C-terminal domain of mouse brain tubby protein · the same entry in another collection · chain A against A, TM-score 1.00
P50586 · AlphaFold monomer V2.0 prediction for tubby protein (P50586) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50586
Elsewhere: RCSB PDB 1C8Z · PDBe 1C8Z · UniProt P50586

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