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Initial crystal structural analysis of a probable kinase from leishmania major friedlin

Analyse Initial crystal structural analysis of a probable kinase from leishmania major… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1Y63
Type: protein
Length: 168 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LMAJ004144AAA protein
UniProt: Q4Q7A6
Ligands: ADP, MN, NA, BR
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LMAJ004144AAA protein	protein	168	52% helix, 15% strand	Q4Q7A6

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
MN · Manganese (II) ion · metal · 8 copies · chains A
NA · Sodium ion · metal · 2 copies · chains A
BR · Bromide ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	337	0.55	0.74	36	MN, BR, ADP

Compared structures

1Y63 · Initial crystal structural analysis of a probable kinase from Leishmania major Friedlin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4Q7A6
Elsewhere: RCSB PDB 1Y63 · PDBe 1Y63 · UniProt Q4Q7A6

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