Research workbench
Pyrr, the regulator of the pyrimidine biosynthetic operon in bacillus caldolyticus, sulfate-bound form
Analyse Pyrr, the regulator of the pyrimidine biosynthetic operon in bacillus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XZN
- Type
- protein
- Length
- 321 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pyrr bifunctional protein
- EC
- 2.4.2.9
- UniProt
- P41007
- Ligands
- MG, SO4
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pyrr bifunctional protein (EC 2.4.2.9) | protein | 161 | 33% helix, 31% strand | P41007 |
| B | Pyrr bifunctional protein (EC 2.4.2.9) | protein | 160 | 34% helix, 29% strand | P41007 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.43 | 0.75 | 24 | MG, SO4 |
| 2 | 103 | 0.40 | 0.76 | 18 | MG, SO4 |
Interfaces
1 interface between chains.
- A–B · 959 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 1XZN · PYRR, THE REGULATOR OF THE PYRIMIDINE BIOSYNTHETIC OPERON IN BACILLUS CALDOLYTICUS… · the same entry in another collection · chain B against B, TM-score 1.00
- P41007 · AlphaFold monomer V2.0 prediction for bifunctional protein pyrr (P41007) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41007
- Elsewhere: RCSB PDB 1XZN · PDBe 1XZN · UniProt P41007
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.