Research workbench
X-ray structure of northeast structural genomics consortium target SFR7
Analyse X-ray structure of northeast structural genomics consortium target SFR7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XSR
- Type
- protein
- Length
- 316 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ureidoglycolate hydrolase
- EC
- 3.5.3.19
- UniProt
- P63487
- Pockets
- 5 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 4% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Ureidoglycolate hydrolase (EC 3.5.3.19) | protein | 158 | 4% helix, 42% strand | P63487 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.54 | 0.80 | 23 | empty |
| 2 | 133 | 0.48 | 0.79 | 19 | empty |
| 3 | 102 | 0.36 | 0.74 | 17 | empty |
| 4 | 66 | 0.32 | 0.75 | 16 | empty |
| 5 | 59 | 0.30 | 0.75 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1689 Ų buried · 17 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 1XSR · X-Ray structure of Northeast Structural Genomics Consortium target SfR7 · the same entry in another collection · chain A against A, TM-score 1.00
- P63487 · AlphaFold monomer V2.0 prediction for ureidoglycolate lyase (P63487) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63487
- Elsewhere: RCSB PDB 1XSR · PDBe 1XSR · UniProt P63487
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