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Crystal structure of RNA-dependent RNA polymerase 3D from human rhinovirus serotype 16
Analyse Crystal structure of RNA-dependent RNA polymerase 3D from human rhinovirus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XR7
- Type
- protein
- Length
- 920 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Genome polyprotein
- EC
- 2.7.7.48
- UniProt
- Q82122
- Pockets
- 7 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Genome polyprotein (EC 2.7.7.48) | protein | 460 | 40% helix, 16% strand | Q82122 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 680 | 0.65 | 0.74 | 62 | empty |
| 2 | 365 | 0.59 | 0.76 | 39 | empty |
| 3 | 417 | 0.57 | 0.74 | 42 | empty |
| 4 | 270 | 0.55 | 0.77 | 28 | empty |
| 5 | 171 | 0.43 | 0.74 | 25 | empty |
Compared structures
- 1XR7 · Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q82122
- Elsewhere: RCSB PDB 1XR7 · PDBe 1XR7 · UniProt Q82122
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