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Crystal structure of inactive F1-mutant G37A

Analyse Crystal structure of inactive F1-mutant G37A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1XQV
Type: protein
Length: 290 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proline iminopeptidase
EC: 3.4.11.5
UniProt: P96084
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proline iminopeptidase (EC 3.4.11.5)	protein	290	46% helix, 19% strand	P96084

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.78	0.98	21	empty
2	160	0.46	0.76	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1XQV · Crystal structure of inactive F1-mutant G37A · the same entry in another collection · chain A against A, TM-score 1.00
P96084 · AlphaFold monomer V2.0 prediction for proline iminopeptidase (P96084) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P96084
Elsewhere: RCSB PDB 1XQV · PDBe 1XQV · UniProt P96084

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