Research workbench
T5 5'-exonuclease mutant K83A
Analyse T5 5'-exonuclease mutant K83A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XO1
- Type
- protein
- Length
- 490 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-exonuclease
- EC
- 3.1.11.3
- UniProt
- P06229
- Pockets
- 5 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 5'-exonuclease (EC 3.1.11.3) | protein | 245 | 56% helix, 12% strand | P06229 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.48 | 0.77 | 32 | empty |
| 2 | 177 | 0.43 | 0.73 | 27 | empty |
| 3 | 104 | 0.40 | 0.76 | 24 | empty |
| 4 | 75 | 0.33 | 0.75 | 13 | empty |
| 5 | 79 | 0.32 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 713 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 1XO1 · T5 5'-exonuclease mutant K83A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06229
- Elsewhere: RCSB PDB 1XO1 · PDBe 1XO1 · UniProt P06229
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