Research workbench
High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA editing ligase 1
Analyse High resolution crystal structure of an editosome enzyme from trypanosoma… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1XDN
- Type
- protein
- Length
- 265 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA editing ligase MP52
- Ligands
- ATP, MG
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA editing ligase MP52 | protein | 265 | 27% helix, 30% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.65 | 0.85 | 34 | MG, ATP |
| 2 | 93 | 0.37 | 0.75 | 19 | empty |
| 3 | 52 | 0.32 | 0.76 | 11 | empty |
Modifications
Observed in the structure: 3 modified (engineered).
Compared structures
- 1XDN · High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1XDN · PDBe 1XDN
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