Research workbench

4M5.3 anti-fluorescein single chain antibody fragment (scfv)

Analyse 4M5.3 anti-fluorescein single chain antibody fragment (scfv) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1X9Q
Type: protein
Length: 231 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 4M5.3 anti-fluorescein single chain antibody fragment
Ligands: FLU
Pockets: 3 · best druggability 0.50

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 51% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	4M5.3 anti-fluorescein single chain antibody fragment	protein	231	8% helix, 51% strand	—

Ligands and binding sites

FLU · 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid · ligand · chains A
ACT · Acetate ion · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	124	0.50	0.80	21	ACT, FLU
2	180	0.49	0.76	29	ACT
3	82	0.33	0.75	16	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1X9Q · 4m5.3 anti-fluorescein single chain antibody fragment (scFv) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1X9Q · PDBe 1X9Q

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