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2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (bphd) from rhodococcus sp. strain RHA1

Analyse 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (bphd) from rhodococcus sp.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1C4X
Type
protein
Length
281 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase)
EC
3.7.1.8
UniProt
O05149
Pockets
2 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase) (EC 3.7.1.8)protein28145% helix, 16% strandO05149

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11460.730.9139empty
2520.280.7513empty

Compared structures

  • 1C4X · 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (bphd) from rhodococcus sp. strain… · the same entry in another collection · chain A against A, TM-score 1.00

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