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Solution structure of the first lim domain of thyroid receptor interacting protein 6 (TRIP6)

Analyse Solution structure of the first lim domain of thyroid receptor interacting… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1X61
Type: protein
Length: 72 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thyroid receptor interacting protein 6
UniProt: Q15654
Ligands: ZN
Pockets: 1 · best druggability 0.26

Structure

solution nmr · 1 distinct chain · 13% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thyroid receptor interacting protein 6	protein	72	13% helix, 17% strand	Q15654

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.26	0.74	14	empty

Compared structures

1X61 · Solution structure of the first LIM domain of thyroid receptor interacting protein 6… · the same entry in another collection · chain A against A, TM-score 1.00
Q15654 · AlphaFold monomer V2.0 prediction for thyroid receptor-interacting protein 6 (Q15654) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15654
Elsewhere: RCSB PDB 1X61 · PDBe 1X61 · UniProt Q15654

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