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Solution structure of rrm domain in splicing factor SF2

Analyse Solution structure of rrm domain in splicing factor SF2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1X4A
Type: protein
Length: 109 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Splicing factor, ARGININE/SERINE-rich 1 (splicing factor 2, alternate splicing factor)…
UniProt: Q07955
Pockets: 1 · best druggability 0.24

Structure

solution nmr · 1 distinct chain · 20% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Splicing factor, ARGININE/SERINE-rich 1 (splicing factor 2, alternate splicing factor) variant	protein	109	20% helix, 21% strand	Q07955

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.24	0.72	11	empty

Compared structures

1X4A · Solution structure of RRM domain in splicing factor SF2 · the same entry in another collection · chain A against A, TM-score 1.00
Q07955 · AlphaFold monomer V2.0 prediction for SERINE/ARGININE-rich splicing factor 1 (Q07955) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q07955
Elsewhere: RCSB PDB 1X4A · PDBe 1X4A · UniProt Q07955

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