Research workbench
Crystal structure of a probable nucleotidyl transferase protein from thermus thermophilus HB8
Analyse Crystal structure of a probable nucleotidyl transferase protein from thermus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1WTY
- Type
- protein
- Length
- 459 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein TTHA0048
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein TTHA0048 | protein | 116 | 78% helix, 0% strand | — |
| B, D | Hypothetical protein TTHA0048 | protein | 114 | 76% helix, 0% strand | — |
| C | Hypothetical protein TTHA0048 | protein | 115 | 77% helix, 0% strand | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 643 | 0.71 | 0.79 | 74 | empty |
| 2 | 53 | 0.29 | 0.75 | 16 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1170 Ų buried · 27 hydrogen bonds · protein-protein
- A–D · 1146 Ų buried · 26 hydrogen bonds · protein-protein
- B–D · 379 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 374 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 274 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 1WTY · Crystal structure of a probable nucleotidyl transferase protein from thermus thermophilus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1WTY · PDBe 1WTY
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