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Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus

Analyse Crystal structure of multiple substrate aminotransferase (msat) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WST
Type: protein
Length: 403 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Multiple substrate aminotransferase
EC: 2.6.1.-
UniProt: Q9V2W5
Ligands: PLP
Pockets: 2 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Multiple substrate aminotransferase (EC 2.6.1.-)	protein	403	48% helix, 15% strand	Q9V2W5

Ligands and binding sites

PLP · Pyridoxal-5'-phosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	443	0.64	0.77	54	PLP
2	50	0.28	0.75	17	empty

Modifications

Observed in the structure: 1 cofactor (pyridoxal phosphate Schiff base).

Compared structures

1WST · Crystal structure of multiple substrate aminotransferase (MsAT) from Thermococcus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9V2W5
Elsewhere: RCSB PDB 1WST · PDBe 1WST · UniProt Q9V2W5

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