Research workbench
Crystal structure of axin dix domain
Analyse Crystal structure of axin dix domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1WSP
- Type
- protein
- Length
- 251 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Axin 1 protein
- Ligands
- BEZ, HG
- Pockets
- 1 · best druggability 0.44
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Axin 1 protein | protein | 83 | 8% helix, 45% strand | — |
| B, C | Axin 1 protein | protein | 84 | 8% helix, 44% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.44 | 0.75 | 27 | empty |
Interfaces
2 interfaces between chains.
- B–C · 852 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 424 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 1WSP · Crystal structure of axin dix domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1WSP · PDBe 1WSP
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