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Refined solution structure of der F 2, the major mite allergen from dermatophagoides farinae

Analyse Refined solution structure of der F 2, the major mite allergen from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WRF
Type: protein
Length: 129 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mite group 2 allergen der F 2
UniProt: Q00855
Pockets: 1 · best druggability 0.76

Structure

solution nmr · 1 distinct chain · 2% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mite group 2 allergen der F 2	protein	129	2% helix, 43% strand	Q00855

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.76	0.96	26	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1WRF · Refined solution structure of Der f 2, The Major Mite Allergen from Dermatophagoides… · the same entry in another collection · chain A against A, TM-score 1.00
Q00855 · AlphaFold monomer V2.0 prediction for mite group 2 allergen der F 2 (Q00855) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q00855
Elsewhere: RCSB PDB 1WRF · PDBe 1WRF · UniProt Q00855

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