Research workbench
Crystal structure of djbp fragment which was obtained by limited proteolysis
Analyse Crystal structure of djbp fragment which was obtained by limited proteolysis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1WLZ
- Type
- protein
- Length
- 335 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cap-binding protein complex interacting protein 1 isoform a
- UniProt
- Q9H5C4
- Pockets
- 4 · best druggability 0.49
Structure
x-ray diffraction · 3 distinct chains · 60% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cap-binding protein complex interacting protein 1 isoform a | protein | 85 | 60% helix, 4% strand | Q9H5C4 |
| B | Cap-binding protein complex interacting protein 1 isoform a | protein | 84 | 60% helix, 6% strand | Q9H5C4 |
| C, D | Cap-binding protein complex interacting protein 1 isoform a | protein | 83 | 61% helix, 6% strand | Q9H5C4 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.49 | 0.82 | 19 | empty |
| 2 | 62 | 0.42 | 0.82 | 17 | empty |
| 3 | 63 | 0.28 | 0.73 | 18 | empty |
| 4 | 52 | 0.25 | 0.72 | 15 | empty |
Interfaces
4 interfaces between chains.
- B–D · 469 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 429 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 400 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 13 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1WLZ · Crystal structure of DJBP fragment which was obtained by limited proteolysis · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H5C4
- Elsewhere: RCSB PDB 1WLZ · PDBe 1WLZ · UniProt Q9H5C4
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