Research workbench

Crystal structure of a glucose-6-phosphate isomerase like protein from thermus thermophilus HB8

Analyse Crystal structure of a glucose-6-phosphate isomerase like protein from thermus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WIW
Type: protein
Length: 565 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucose-6-phosphate isomerase like protein
UniProt: Q5SIM3
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 42% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glucose-6-phosphate isomerase like protein	protein	282	42% helix, 13% strand	Q5SIM3
B	Glucose-6-phosphate isomerase like protein	protein	283	43% helix, 14% strand	Q5SIM3

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	875	0.78	0.80	83	empty
2	107	0.39	0.75	23	empty

Interfaces

1 interface between chains.

A–B · 1812 Å² buried · 23 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

1WIW · Crystal structure of a glucose-6-phosphate isomerase like protein from thermus… · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SIM3
Elsewhere: RCSB PDB 1WIW · PDBe 1WIW · UniProt Q5SIM3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.