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Solution structure of the ring finger domain of the human KIAA1045 protein

Analyse Solution structure of the ring finger domain of the human KIAA1045 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WIL
Type: protein
Length: 89 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KIAA1045 protein
UniProt: Q9UPV7
Ligands: ZN
Pockets: 2 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 8% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	KIAA1045 protein	protein	89	8% helix, 0% strand	Q9UPV7

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	137	0.41	0.74	17	empty
2	66	0.28	0.73	20	empty

Compared structures

1WIL · Solution Structure of the RING Finger Domain of the Human KIAA1045 Protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9UPV7 · AlphaFold monomer V2.0 prediction for phd finger protein 24 (Q9UPV7) · a predicted model of the same protein · chain A against A, TM-score 0.48

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UPV7
Elsewhere: RCSB PDB 1WIL · PDBe 1WIL · UniProt Q9UPV7

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