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Solution structure of pleckstrin homology domain from human KIAA1058 protein

Analyse Solution structure of pleckstrin homology domain from human KIAA1058 protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WG7
Type: protein
Length: 150 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dedicator of cytokinesis protein 9
UniProt: Q9BZ29
Pockets: 1 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 21% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dedicator of cytokinesis protein 9	protein	150	21% helix, 25% strand	Q9BZ29

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	186	0.49	0.76	23	empty

Compared structures

1WG7 · Solution structure of pleckstrin homology domain from human KIAA1058 protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9BZ29 · AlphaFold monomer V2.0 prediction for dedicator of cytokinesis protein 9 (Q9BZ29) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BZ29
Elsewhere: RCSB PDB 1WG7 · PDBe 1WG7 · UniProt Q9BZ29

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