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Solution structure of the RAS-binding domain of mouse RGS14

Analyse Solution structure of the RAS-binding domain of mouse RGS14 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1WFY
Type: protein
Length: 104 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Regulator of G-protein signaling 14
UniProt: P97492
Pockets: 1 · best druggability 0.58

Structure

solution nmr · 1 distinct chain · 7% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Regulator of G-protein signaling 14	protein	104	7% helix, 18% strand	P97492

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	267	0.58	0.78	27	empty

Compared structures

1WFY · Solution structure of the Ras-binding domain of mouse RGS14 · the same entry in another collection · chain A against A, TM-score 1.00
P97492 · AlphaFold monomer V2.0 prediction for regulator of G-protein signaling 14 (P97492) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P97492
Elsewhere: RCSB PDB 1WFY · PDBe 1WFY · UniProt P97492

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