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Third lrr domain of drosophila slit

Analyse Third lrr domain of drosophila slit in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1W8A
Type: protein
Length: 189 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Slit protein
UniProt: P24014
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Slit protein	protein	189	12% helix, 16% strand	P24014

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.42	0.83	14	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1W8A · Third LRR domain of Drosophila Slit · the same entry in another collection · chain A against A, TM-score 1.00
P24014 · AlphaFold monomer V2.0 prediction for protein slit (P24014) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P24014
Elsewhere: RCSB PDB 1W8A · PDBe 1W8A · UniProt P24014

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