Research workbench
Complex of vancomycin with D-lactic acid
Analyse Complex of vancomycin with D-lactic acid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1C0R
- Type
- protein
- Length
- 14 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vancomycin
- Ligands
- RER, LAC, BGC, CL
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Vancomycin | protein | 7 | 0% helix, 14% strand | — |
Ligands and binding sites
- RER · vancosamine · ligand · 2 copies · chains A, B
- LAC · Lactic acid · ligand · chains B
- BGC · beta-D-glucopyranose · sugar · 2 copies · chains A, B
- CL · Chloride ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 191 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified, 2 glycan (nonstandard, glycosylation).
Compared structures
- 1C0R · Complex of vancomycin with D-lactic acid · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1C0R · PDBe 1C0R
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