Research workbench
Xylose isomerase from thermus thermophilus
Analyse Xylose isomerase from thermus thermophilus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1BXB
- Type
- protein
- Length
- 1,548 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Xylose isomerase
- EC
- 5.3.1.5
- UniProt
- P26997
- Pockets
- 20 · best druggability 0.87
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Xylose isomerase (EC 5.3.1.5) | protein | 387 | 50% helix, 10% strand | P26997 |
Pockets
20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1033 | 0.87 | 0.88 | 111 | empty |
| 2 | 1171 | 0.85 | 0.86 | 114 | empty |
| 3 | 211 | 0.83 | 0.96 | 57 | empty |
| 4 | 169 | 0.82 | 0.97 | 48 | empty |
| 5 | 51 | 0.71 | 0.99 | 17 | empty |
Interfaces
6 interfaces between chains.
- A–C · 4531 Ų buried · 66 hydrogen bonds · protein-protein
- B–D · 4526 Ų buried · 63 hydrogen bonds · protein-protein
- B–C · 1952 Ų buried · 39 hydrogen bonds · protein-protein
- A–D · 1948 Ų buried · 40 hydrogen bonds · protein-protein
- C–D · 1613 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26997
- Elsewhere: RCSB PDB 1BXB · PDBe 1BXB · UniProt P26997
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