Research workbench
Structure of an activated dictyostelium STAT in its DNA-unbound form
Analyse Structure of an activated dictyostelium STAT in its DNA-unbound form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1UUS
- Type
- protein
- Length
- 465 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- STAT protein
- UniProt
- O00910
- Pockets
- 6 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | STAT protein | protein | 465 | 38% helix, 20% strand | O00910 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 502 | 0.64 | 0.76 | 54 | empty |
| 2 | 186 | 0.45 | 0.74 | 21 | empty |
| 3 | 110 | 0.39 | 0.75 | 20 | empty |
| 4 | 82 | 0.36 | 0.76 | 21 | empty |
| 5 | 111 | 0.34 | 0.72 | 20 | empty |
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1UUS · Structure of an activated Dictyostelium STAT in its DNA-unbound form · the same entry in another collection · chain A against A, TM-score 1.00
- O00910 · AlphaFold monomer V2.0 prediction for signal transducer and activator of transcription a… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00910
- Elsewhere: RCSB PDB 1UUS · PDBe 1UUS · UniProt O00910
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