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Structure of an activated dictyostelium STAT in its DNA-unbound form

Analyse Structure of an activated dictyostelium STAT in its DNA-unbound form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1UUR
Type
protein
Length
461 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Stata protein
UniProt
O00910
Pockets
5 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AStata proteinprotein46140% helix, 20% strandO00910

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14790.640.7753empty
21760.480.7628empty
31500.420.7420empty
41030.400.7619empty
5550.300.7512empty

Modifications

Observed in the structure: 1 modified (phosphorylation).

Compared structures

  • 1UUR · Structure of an activated Dictyostelium STAT in its DNA-unbound form · the same entry in another collection · chain A against A, TM-score 1.00
  • O00910 · AlphaFold monomer V2.0 prediction for signal transducer and activator of transcription a… · a predicted model of the same protein · chain A against A, TM-score 0.99

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