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Crystal structure of the RNA binding domain of bluetongue virus non- structural protein 2(NS2)
Analyse Crystal structure of the RNA binding domain of bluetongue virus non- structural… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1UTY
- Type
- protein
- Length
- 306 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural protein 2
- EC
- 2.7.7.48
- UniProt
- P23065
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 10% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Non-structural protein 2 (EC 2.7.7.48) | protein | 153 | 10% helix, 44% strand | P23065 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 496 | 0.67 | 0.78 | 65 | empty |
| 2 | 60 | 0.44 | 0.82 | 13 | empty |
| 3 | 89 | 0.36 | 0.75 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 1966 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
- 1UTY · Crystal structure of the RNA binding domain of Bluetongue virus non-structural protein… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23065
- Elsewhere: RCSB PDB 1UTY · PDBe 1UTY · UniProt P23065
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