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MONA/GADS SH3C in complex with hpk derived peptide

Analyse MONA/GADS SH3C in complex with hpk derived peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1UTI
Type: protein
Length: 73 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GRB2-related adaptor protein 2; Mitogen-activated protein kinase kinase kinase kinase 1
EC: 2.7.1.37
UniProt: O89100, P70218

Structure

x-ray diffraction · 2 distinct chains · 10% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GRB2-related adaptor protein 2	protein	57	5% helix, 49% strand	O89100
D	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.1.37)	protein	16	25% helix, 0% strand	P70218

Interfaces

1 interface between chains.

A–D · 565 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

1UTI · Mona/Gads SH3C in complex with HPK derived peptide · the same entry in another collection · chain A against A, TM-score 1.00
O89100 · AlphaFold monomer V2.0 prediction for GRB2-related adaptor protein 2 (O89100) · a predicted model of the same protein · chain A against A, TM-score 0.96
P70218 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase kinase… · a predicted model of the same protein · chain D against A, TM-score 0.31

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O89100
Every structure of UniProt P70218
Elsewhere: RCSB PDB 1UTI · PDBe 1UTI · UniProt O89100 · UniProt P70218

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