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Inosamine-phosphate amidinotransferase STRB1 from streptomyces griseus

Analyse Inosamine-phosphate amidinotransferase STRB1 from streptomyces griseus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1BWD
Type: protein
Length: 696 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (inosamine-phosphate amidinotransferase)
EC: 2.1.4.2
UniProt: P08078
Pockets: 4 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein (inosamine-phosphate amidinotransferase) (EC 2.1.4.2)	protein	348	26% helix, 23% strand	P08078

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.71	0.85	40	empty
2	307	0.71	0.85	41	empty
3	81	0.45	0.81	18	empty
4	76	0.44	0.81	19	empty

Compared structures

1BWD · Inosamine-phosphate amidinotransferase STRB1 from streptomyces griseus · the same entry in another collection · chain A against A, TM-score 1.00
P08078 · AlphaFold monomer V2.0 prediction for inosamine-phosphate amidinotransferase 1 (P08078) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08078
Elsewhere: RCSB PDB 1BWD · PDBe 1BWD · UniProt P08078

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