Research workbench
Structure of the endoglucanase CEL6 from mycobacterium tuberculosis in complex with thiocellopentaose at 1.1 ångström
Analyse Structure of the endoglucanase CEL6 from mycobacterium tuberculosis in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1UOZ
- Type
- protein
- Length
- 300 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative cellulase
- UniProt
- O53607
- Ligands
- SSG, GLC, SGC, SO4
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative cellulase | protein | 300 | 37% helix, 13% strand | O53607 |
Ligands and binding sites
- SSG · 1,4-dithio-beta-D-glucopyranose · ligand · 2 copies · chains A
- GLC · alpha-D-glucopyranose · sugar · chains A
- SGC · 4-thio-beta-D-glucopyranose · ion
- SO4 · Sulfate ion · ion · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 248 | 0.64 | 0.82 | 37 | SSG, GLC, GOL |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1UOZ · Structure of the endoglucanase Cel6 from Mycobacterium tuberculosis in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O53607
- Elsewhere: RCSB PDB 1UOZ · PDBe 1UOZ · UniProt O53607
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.