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Solution structure of rsgi ruh-007, PDZ domain in human cdna

Analyse Solution structure of rsgi ruh-007, PDZ domain in human cdna in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1UM1
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KIAA1849 protein
UniProt: Q96JH8
Pockets: 1 · best druggability 0.45

Structure

solution nmr · 1 distinct chain · 19% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	KIAA1849 protein	protein	110	19% helix, 28% strand	Q96JH8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.45	0.79	22	empty

Compared structures

1UM1 · Solution Structure of RSGI RUH-007, PDZ domain in Human cDNA · the same entry in another collection · chain A against A, TM-score 1.00
Q96JH8 · AlphaFold monomer V2.0 prediction for RAS-associating and dilute domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96JH8
Elsewhere: RCSB PDB 1UM1 · PDBe 1UM1 · UniProt Q96JH8

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