Research workbench

Crystal structure of dsbdgamma

Analyse Crystal structure of dsbdgamma in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1UC7
Type: protein
Length: 248 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: THIOL:DISULFIDE interchange protein dsbd
EC: 1.8.1.8
UniProt: P58162
Pockets: 2 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	THIOL:DISULFIDE interchange protein dsbd (EC 1.8.1.8)	protein	124	40% helix, 21% strand	P58162

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	712	0.72	0.79	35	empty
2	54	0.37	0.80	16	empty

Interfaces

1 interface between chains.

A–B · 651 Å² buried · 16 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1UC7 · Crystal structure of DsbDgamma · the same entry in another collection · chain A against A, TM-score 1.00
P58162 · AlphaFold monomer V2.0 prediction for THIOL:DISULFIDE interchange protein dsbd (P58162) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P58162
Elsewhere: RCSB PDB 1UC7 · PDBe 1UC7 · UniProt P58162

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.