Research workbench
Crystal structure of the fatty ACID/PHOSPHOLIPID synthesis protein plsx from enterococcus faecalis V583
Analyse Crystal structure of the fatty ACID/PHOSPHOLIPID synthesis protein plsx from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1U7N
- Type
- protein
- Length
- 636 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty ACID/PHOSPHOLIPID synthesis protein plsx
- UniProt
- Q82ZE8
- Pockets
- 7 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 48% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty ACID/PHOSPHOLIPID synthesis protein plsx | protein | 318 | 48% helix, 17% strand | Q82ZE8 |
| B | Fatty ACID/PHOSPHOLIPID synthesis protein plsx | protein | 318 | 48% helix, 17% strand | Q82ZE8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 682 | 0.68 | 0.76 | 78 | EOH |
| 2 | 468 | 0.64 | 0.77 | 51 | empty |
| 3 | 185 | 0.59 | 0.81 | 22 | EOH |
| 4 | 57 | 0.35 | 0.78 | 15 | empty |
| 5 | 72 | 0.33 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1826 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 26 modified (engineered).
Compared structures
- 1U7N · Crystal Structure of the fatty acid/phospholipid synthesis protein PlsX from Enterococcus… · the same entry in another collection · chain A against A, TM-score 1.00
- Q82ZE8 · AlphaFold monomer V2.0 prediction for phosphate acyltransferase (Q82ZE8) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q82ZE8
- Elsewhere: RCSB PDB 1U7N · PDBe 1U7N · UniProt Q82ZE8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.