Research workbench
The crystal structure of acetyltransferase
Analyse The crystal structure of acetyltransferase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1U6M
- Type
- protein
- Length
- 756 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetyltransferase, gnat family
- UniProt
- Q836Z8
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Acetyltransferase, gnat family | protein | 189 | 38% helix, 28% strand | Q836Z8 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 8 copies · chains A, C, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 855 | 0.76 | 0.79 | 85 | SO4 |
| 2 | 618 | 0.75 | 0.81 | 61 | SO4 |
| 3 | 355 | 0.66 | 0.80 | 49 | empty |
| 4 | 464 | 0.66 | 0.78 | 48 | SO4 |
| 5 | 471 | 0.63 | 0.76 | 42 | SO4 |
Interfaces
4 interfaces between chains.
- B–D · 726 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 653 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 361 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 185 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1U6M · The crystal structure of acetyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q836Z8
- Elsewhere: RCSB PDB 1U6M · PDBe 1U6M · UniProt Q836Z8
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