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Hfq protein from pseudomonas aeruginosa. high-salt crystals

Analyse Hfq protein from pseudomonas aeruginosa. high-salt crystals in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1U1T
Type: protein
Length: 398 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hfq protein
UniProt: Q9HUM0
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 4 distinct chains · 20% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, D	Hfq protein	protein	66	20% helix, 45% strand	Q9HUM0
B, F	Hfq protein	protein	66	20% helix, 44% strand	Q9HUM0
C	Hfq protein	protein	65	20% helix, 45% strand	Q9HUM0
E	Hfq protein	protein	69	19% helix, 43% strand	Q9HUM0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	917	0.71	0.75	67	empty

Interfaces

6 interfaces between chains.

D–E · 807 Å² buried · 11 hydrogen bonds · protein-protein
A–F · 784 Å² buried · 11 hydrogen bonds · protein-protein
C–D · 777 Å² buried · 11 hydrogen bonds · protein-protein
E–F · 725 Å² buried · 11 hydrogen bonds · protein-protein
A–B · 720 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

1U1T · Hfq protein from Pseudomonas aeruginosa. High-salt crystals · the same entry in another collection · chain F against F, TM-score 1.00
Q9HUM0 · AlphaFold monomer V2.0 prediction for RNA-binding protein hfq (Q9HUM0) · a predicted model of the same protein · chain C against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HUM0
Elsewhere: RCSB PDB 1U1T · PDBe 1U1T · UniProt Q9HUM0

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