Research workbench

Heterogeneous nuclear ribonucleoprotein (hnrnp) C oligomerization domain tetramer

Analyse Heterogeneous nuclear ribonucleoprotein (hnrnp) C oligomerization domain… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1TXP
Type: protein
Length: 112 residues
Chains: 4
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heterogeneous nuclear ribonucleoprotein C protein
UniProt: Q86U45
Pockets: 2 · best druggability 0.51

Structure

solution nmr · 1 distinct chain · 82% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Heterogeneous nuclear ribonucleoprotein C protein	protein	28	82% helix, 0% strand	Q86U45

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.51	0.83	18	empty
2	52	0.25	0.73	17	empty

Interfaces

6 interfaces between chains.

B–C · 668 Å² buried · 3 hydrogen bonds · protein-protein
A–D · 636 Å² buried · 2 hydrogen bonds · protein-protein
A–B · 615 Å² buried · 2 hydrogen bonds · protein-protein
C–D · 539 Å² buried · 2 hydrogen bonds · protein-protein
B–D · 113 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1TXP · Heterogeneous Nuclear Ribonucleoprotein (hnRNP) C Oligomerization Domain Tetramer · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86U45
Elsewhere: RCSB PDB 1TXP · PDBe 1TXP · UniProt Q86U45

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.