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Crystal structure of the extracellular domain of the type II activin receptor

Analyse Crystal structure of the extracellular domain of the type II activin receptor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1BTE
Type: protein
Length: 186 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (activin receptor type II)
EC: 2.7.1.-
UniProt: P27038
Ligands: NAG

Structure

x-ray diffraction · 2 distinct chains · 8% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (activin receptor type II) (EC 2.7.1.-)	protein	92	8% helix, 45% strand	P27038
B	Protein (activin receptor type II) (EC 2.7.1.-)	protein	94	7% helix, 44% strand	P27038

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 10 disulfide, 4 glycan (disulfide, N-glycosylation).

Compared structures

1BTE · Crystal structure of the extracellular domain of the type II activin receptor · the same entry in another collection · chain A against A, TM-score 1.00
P27038 · AlphaFold monomer V2.0 prediction for activin receptor type-2A (P27038) · a predicted model of the same protein · chain B against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27038
Elsewhere: RCSB PDB 1BTE · PDBe 1BTE · UniProt P27038

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