Research workbench
Endoglucanase CEL5G from pseudoalteromonas haloplanktis in complex with cellobiose
Analyse Endoglucanase CEL5G from pseudoalteromonas haloplanktis in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1TVP
- Type
- protein
- Length
- 584 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellulase
- EC
- 3.2.1.4
- UniProt
- O86099
- Ligands
- BGC
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cellulase (EC 3.2.1.4) | protein | 293 | 39% helix, 20% strand | O86099 |
| B | Cellulase (EC 3.2.1.4) | protein | 291 | 38% helix, 21% strand | O86099 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · 2 copies · chains B
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 495 | 0.76 | 0.84 | 58 | EPE |
| 2 | 110 | 0.41 | 0.76 | 18 | empty |
| 3 | 107 | 0.40 | 0.76 | 18 | BGC |
Interfaces
1 interface between chains.
- A–B · 706 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 1TVP · Endoglucanase cel5G from Pseudoalteromonas haloplanktis in complex with cellobiose · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O86099
- Elsewhere: RCSB PDB 1TVP · PDBe 1TVP · UniProt O86099
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