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F1-G module pair residues 1-91 (C83S) of tissue-type plasminogen activator (T-pa) (NMR, 298K, PH2.95, representative structure)

Analyse F1-G module pair residues 1-91 (C83S) of tissue-type plasminogen activator… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1TPG
Type: protein
Length: 91 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: T-plasminogen activator F1-G
EC: 3.4.21.68
UniProt: P00750
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 0% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	T-plasminogen activator F1-G (EC 3.4.21.68)	protein	91	0% helix, 32% strand	P00750

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.36	0.75	15	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1TPG · F1-G module pair residues 1-91 (C83S) of tissue-type plasminogen activator (T-pa) (NMR… · the same entry in another collection · chain A against A, TM-score 1.00
P00750 · AlphaFold monomer V2.0 prediction for tissue-type plasminogen activator (P00750) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00750
Elsewhere: RCSB PDB 1TPG · PDBe 1TPG · UniProt P00750

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