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Crystal structural analysis of tobacco necrosis virus (tnv) at 5 ångströms resolution

Analyse Crystal structural analysis of tobacco necrosis virus (tnv) at 5 ångströms… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1TNV
Type: protein
Length: 582 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tobacco necrosis virus (subunit VP1); Tobacco necrosis virus (subunit VP3)
Pockets: 9 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 12% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Tobacco necrosis virus (subunit VP1)	protein	186	11% helix, 28% strand	—
C	Tobacco necrosis virus (subunit VP3)	protein	210	13% helix, 26% strand	—

Pockets

9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	672	0.72	0.80	106	empty
2	557	0.69	0.79	99	empty
3	493	0.68	0.80	84	empty
4	290	0.61	0.80	57	empty
5	189	0.56	0.81	39	empty

Interfaces

3 interfaces between chains.

A–C · 212 Å² buried · 1 hydrogen bond · protein-protein
B–C · 184 Å² buried · 4 hydrogen bonds · protein-protein
A–B · 158 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1TNV · Crystal structural analysis of tobacco necrosis virus (tnv) at 5 ångströms resolution · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1TNV · PDBe 1TNV

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