Research workbench
Three-dimensional structure of theiler murine encephalomyelitis virus (bean strain)
Analyse Three-dimensional structure of theiler murine encephalomyelitis virus (bean… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1TMF
- Type
- protein
- Length
- 806 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- THEILER'S murine encephalomyelitis virus (subunit VP1); THEILER'S murine…
- UniProt
- P08544, P13899
- Pockets
- 11 · best druggability 0.80
Structure
x-ray diffraction · 4 distinct chains · 3% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | THEILER'S murine encephalomyelitis virus (subunit VP1) | protein | 276 | 0% helix, 17% strand | P08544 |
| 2 | THEILER'S murine encephalomyelitis virus (subunit VP2) | protein | 267 | 5% helix, 30% strand | P08544 |
| 3 | THEILER'S murine encephalomyelitis virus (subunit VP3) | protein | 232 | 3% helix, 24% strand | P08544 |
| 4 | THEILER'S murine encephalomyelitis virus (subunit VP4) | protein | 31 | 13% helix, 0% strand | P13899 |
Pockets
11 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.80 | 0.96 | 33 | empty |
| 2 | 594 | 0.77 | 0.84 | 79 | empty |
| 3 | 800 | 0.76 | 0.80 | 66 | empty |
| 4 | 88 | 0.73 | 0.96 | 18 | empty |
| 5 | 317 | 0.59 | 0.77 | 39 | empty |
Interfaces
6 interfaces between chains.
- 1–2 · 2388 Ų buried · 33 hydrogen bonds · protein-protein
- 1–3 · 1423 Ų buried · 18 hydrogen bonds · protein-protein
- 2–3 · 810 Ų buried · 10 hydrogen bonds · protein-protein
- 1–4 · 453 Ų buried · 7 hydrogen bonds · protein-protein
- 3–4 · 267 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 1TMF · Three-dimensional structure of theiler murine encephalomyelitis virus (bean strain) · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08544
- Every structure of UniProt P13899
- Elsewhere: RCSB PDB 1TMF · PDBe 1TMF · UniProt P08544 · UniProt P13899
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