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X-ray structure of the human alpha-actinin isoform 3 at 2.2A resolution

Analyse X-ray structure of the human alpha-actinin isoform 3 at 2.2A resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1TJT
Type: protein
Length: 224 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-actinin 3
UniProt: Q08043
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 60% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-actinin 3	protein	224	60% helix, 2% strand	Q08043

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	95	0.39	0.76	17	empty

Compared structures

1TJT · X-ray structure of the human alpha-actinin isoform 3 at 2.2A resolution · the same entry in another collection · chain A against A, TM-score 1.00
Q08043 · AlphaFold monomer V2.0 prediction for alpha-actinin-3 (Q08043) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08043
Elsewhere: RCSB PDB 1TJT · PDBe 1TJT · UniProt Q08043

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