Research workbench
Structure of human SENP2
Analyse Structure of human SENP2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1TH0
- Type
- protein
- Length
- 449 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sentrin-specific protease 2
- EC
- 3.4.22.-
- UniProt
- Q9HC62
- Pockets
- 4 · best druggability 0.54
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sentrin-specific protease 2 (EC 3.4.22.-) | protein | 226 | 46% helix, 16% strand | Q9HC62 |
| B | Sentrin-specific protease 2 (EC 3.4.22.-) | protein | 223 | 45% helix, 17% strand | Q9HC62 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 205 | 0.54 | 0.78 | 25 | empty |
| 2 | 106 | 0.37 | 0.74 | 19 | empty |
| 3 | 105 | 0.37 | 0.74 | 16 | empty |
| 4 | 65 | 0.32 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 267 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HC62
- Elsewhere: RCSB PDB 1TH0 · PDBe 1TH0 · UniProt Q9HC62
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